- AIRLINES BY NAMES
- S
- SN - Sabena - Website details the airline's bankruptcy
- FA - Safair - South Africa - Passenger and cargo flights with 727s, MD80s and Hercules L382Gs
- S2 - Sahara India Airlines - India - Domestic airline flies B737-400s and helicopters
- ---- - Sakhalinskie Aviatrassy (SAT) - Russia - Connects Sakhalin Island with Japan, Korea, China and eastern Russia
- E5 - Samara Airlines - Russia - Domestic flights on Tupolevs, Ilushyns, Yakolevs and Antonovs
RZ - Sansa - Costa Rica - One of Grupo Taca's regional airlines. Fifteen domestic destinations- ---- - Santa Barbara Airlines - Venezuela - Caracas to Madrid, Tenerife and Quito
- SK - SAS - Sweden - Boeings and MDs to North America, Europe and Asia
- SP - SATA - Portugal - Includes Sata Air Acores, Sata Internacional, Sata Express and Azores Express
- SP - Sata Air Açores - Portugal - Flights between the islands, and to Toronto, Boston, Lisbon, Porto and Madeira
- SV - Saudi Arabian Airlines - 126 planes connect the Arabian Peninsula to major world destinations
- ---- - Sayakhat Airlines - Russia - Cargo (Ilyushin 76TD) and passenger (Tupolev 154M) flights
- CB - Scot Airways - Scotland - Used to be Suckling Airways
- SE - Seair - Philippines - A complete domestic schedule, plus an amphibean Dornier DO-24 for charter
- SG - Sempati Air - Indonesia - A Fokker 70
- ---- - Servicios Aéreos Profesionales - Dominican Republic - Throughout the Caribbean, Florida, Yucatan and Venezuela
- NL - Shaheen Air International - Pakistan - Karachi, Islamabad, Lahore and Peshawar, plus Abu Dhabi, Dubai, Kuwait, Alain and Muscat
- SC - Shandong Airline - China - Domestic flights on 737s and SAAB-340s
- FM - Shanghai Airlines - China - Boeing 737s, 757s, and 767s to major Asian and European destinations
- 3S - Shuswap Air - Canada - Charters a Beech King from Salmon Arm, BC
- S5 - Shuttle America - USA - Dash 8s in the northeast US
- S7 - Siberia Airlines - Russia - International and domestic service on Tupolevs and Ilushyns
- 3U - Sichuan Airlines - China - Connects Sichuan province to the rest of China
- MI - Silk Air - Singapore - This regional wing of Singapore Airlines flies A320s
- SQ - Singapore Airlines - 747s and 777s to world destinations
- 5U - Skagway Air Service - USA - Daily flights between Juneau and Skagway, Alaska
- SK - Skyline Airways - Nepal - Domestic flights
- SSV - Skyservice - Canada - From Toronto to holiday destinations
- NP - Skytrans Airlines - Australia - Various small aircraft perform scheduled and charter duties in Queensland
- VW - Skyways - Sweden - Domestic partner of SAS uses Saabs, Fokkers and Jetstreams
- AN - Skywest - Australia - Extensive domestic routes in western Australia. Based in Perth
- YT - Skywest - USA - Brasilia EMB-120s and Canadair Regionals out of Salt Lake City, LAX and San Francisco
- 6Q - Slovak Airlines - Slovakia - TU-154 and B737 service from Bratislava to Brussels and Moscow
- Q7 - Sobel Air - Belgium - A charter remnant of Sabena
- IE - Solomon Airlines - Solomon Islands - To Australia and neighbouring islands on B737s, three Islanders, and two Twin Otters
- DL - Song - USA - Delta's low cost carrier
- 4Z - South African Airlink - South Africa - Embraers and Jetstreams feed the parent airline
- SA - South African Airways - Flag carrier
- YB - South African Express Airways - Connector flights centered in Johannsburg
- M2 - Southeast Air Freight - Bahamas - Daily scheduled freight service between Nassau and Freeport
- QF - Southern Australia Airlines - Qantas-owned regional airline based in Victoria
- A4 - Southern Winds - Argentina - Buenos Aires to points in Argentina, and Madrid to points in Spain and Europe
- WN - Southwest Airlines - USA - 737s to 54 domestic destinations
- NR - Spanair - Spain - Domestic flights plus major South American and European destinations
- ---- - Spirit Airlines - Australia - No-frills domestic flights
- IM - Spirit Airlines - USA - Flights between Florida and the northeast
- UL - SriLankan - Sri Lanka - Flag carrier goes to Europe, Asia and the Middle East. Previously "AirLanka"
- FS - Staf Cargo Airlines - USA - DC-10 and 747 freighters from Miami to South America
- NB - Sterling - Denmark - Low-cost flight from Copenhagen and Stockholm to Mediterranean hotspots
- SD - Sudan Airways - Sudan - B707s, B737s and an A300
- 2S - Sun Air - Fiji - Domestic flights on De Havillands and Beechcraft out of Nadi International Airport
- BU - Sun Air - South Africa - Flights between Johannesburg, Cape Town and Durban
- EZ - Sun Air - Denmark - Jetstreams between Sweden, Norway, Ireland and Germany
- SY - Sun Country Airlines - USA - Low fares from Minneapolis/St. Paul to holiday destinations, plus charters
- JX - SunJet - USA - Twenty daily flights between New York and Florida
- ---- - Sunrise Airlines - USA - Arizona, Utah and Nevada
- PY - Surinam Airways - Surinam
- W3 - Swiftair - Spain - Flies cargo for DHL
- LX - Swiss International Airlines - Switzerland - Worldwide destinations. Was Crossair
- SO - Swiss World - Switzerland - Geneva to Montreal, Newark and Miami
- RB - Syrianair - Syria - A320s, B727s and B747s to major European and Middle East capitals
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